July 2, 2009

Standard Cancer Drugs Do Little to Help Victims of Mesothelioma, but Gene Therapy Could Provide a Beneficial Treatment

Filed under: Health Tips, Science Hall — admin @ 12:48 am

Cancer doctors decide what type of treatment to prescribe with every patient. There are numerous options. There is no standard treatment course for malignant mesothelioma cancer patients. Mesotheliomas lack of agreed-upon treatment is due to low a treatment success rate, rareness, a high mortality rate and a small number of studies providing meaningful stats.

While prospects for patients with mesothelioma have been bleak, doctors have been making progress. Treatments for cancer are traditionally surgery (taking out the tumor and surrounding tissue), chemotherapy (poisoning cancerous cells) and radiation (killing cancer cells with radiation) All three methods have problems. Mesothelioma patients treated with traditional radiation therapy have not responded well to it. In hopes to lessen damage to healthy tissue, researches are studying ways to aim radiation right at the tumor.

The mesothelial tissue around the tumor is removed by surgery. The surgery is difficult and challenging, with unknown effects or benefits to patients. The usual chemotherapy cocktails effective on other cancers are not effective on mesothelioma, and different combinations of chemotherapy drugs have been tried without a lot of success. As with radiation, research is going toward controlling the physical location of the treatment with emphasis on the pleural cavity.

The death rate for mesothelioma is so high that many of even the most sophisticated techniques in cancer treatment are tried out on patients. These include biologic therapy such as the agent interleukin 2 and anti-angiogenesis drugs such as thalidomide. Pemetrexed (Alimta) is a new drug that has shown results in extending life.

Considered by oncologists is where the tumor is located, what stage the mesothelioma is in, and the age and health of the patient. Theres also photodynamic therapy and gene therapy ” two far-out new ways of attacking cancer. Mesothelioma patients sometimes become involved in clinical trials in this area, and see benefits.

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